The Game represents the fundamental characteristics of any meme.
RULE: Whenever you think about this meme, you can tell everyone.
The Game is actually antimemetic, because it defines thinking about The Game as loss, and it also causes the loss of those you tell.
Successful memes usually provide some kind of reward for telling other people, this can be as simple as them being interested in what you are saying. Some memes use punishment as a tactic for replication:
The Religion Game.
RULE: Whenever you think about your religion, tell people about it and you will be given eternal happiness. If you do not tell people about it you risk eternal pain.
The rules for a truly memetic game, the Meme Game, would be something like:
RULE 1: You are playing the Meme Game.
RULE 2: Whenever you think about the Meme Game, you win.
RULE 3: Whenever you win you should tell everyone.